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Boosting Brain and Body in Extreme Heat

Laboratory/Research FacilityFriday, July 17, 2026

Special operation forces often find themselves in extreme conditions, where staying sharp and physically fit is crucial. When the body heats up, the brain can suffer, leading to decreased performance. Researchers explored whether a specific supplement, ketone monoester, could help improve cognitive and physical abilities in intense heat.

In a recent study, 17 trained male athletes took part in a randomized trial. They ingested a combination of caffeine and either ketone monoester or a carbohydrate control before undergoing 90 minutes of intense treadmill exercise in hot conditions. The goal was to assess how well they performed on cognitive tests, as well as their physical endurance.

The results showed that those who took ketone monoester performed better in certain cognitive tasks, such as working memory, compared to those who had the carbohydrate control. Specifically, ketone monoester improved accuracy in 1-back tasks and increased overall target discrimination. However, it didn't make a difference in other cognitive tests like reaction time or object hit and avoid tasks.

Physically, the ketone monoester group lasted longer during a high-intensity exercise test, with an average time of 8.9 minutes compared to 7.0 minutes for the control group. Despite these performance differences, the heart rates and core body temperatures of both groups were similar, suggesting that ketone monoester didn't affect cardiovascular or thermal strain.

The study suggests that combining ketone monoester with caffeine may support specific aspects of cognitive and physical performance during prolonged exercise in extreme heat. However, more research is needed to understand the full benefits and limitations of this supplement.

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