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Why Deleting FTO in Endothelial Cells Could Help Pulmonary Arterial Hypertension

January 28, 2025

Pulmonary arterial hypertension (PAH) is a serious condition where the blood pressure in the lungs is too high. This puts a lot of strain on the heart and can lead to heart failure and even death. A protein called FTO, which is linked to obesity and metabolism, may play a part in PAH, but its role i

science

Unveiling New Ways to Spot FTO in Action

December 24, 2024

Methylation is like a secret code that cells use to control important processes. The most common type is N6-methyladenosine (m6A), found in RNA. Methyltransferases add m6A, and demethylases remove it. The FTO (fat mass and obesity-associated protein) is a demethylase that can malfunction and cause d

health

Weight Issues: A Mix of Mind, Habits, and Genes

December 14, 2024

Ever wondered why some people gain weight easily, while others don't? It's a complex mix of our habits, mental state, and even our genes. A small study looked into this by focusing on young adult women who were either overweight or normal weight. They found that certain changes in a gene called FTO

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